Personally, I find Cognitive Sciences' close vote message "Questions about the behavior of an individual person are off-topic. If you are concerned about a potential medical issue, please seek the advice of a medical professional. For more information, see Why was my self-help question closed as off-topic?" a particularly well-formulated 'self-help' close vote reason.
However, there are borderline questions that pop up quite regularly, where people share their personal account about phenomenon X, and then finalize the question with something like "Is condition X normal / rare / investigated / recognized / ...some other generalized term?"
I find these questions hard to assess for their merits, and particularly difficult to decide whether to vote for question closure, because OP does his or her best to generalize the question. However, the larger part of the question often is a very personal account, and hence, quite anecdotal in nature.
A recent example (where I, reluctantly, voted to leave open):